Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22795105 | 0.81 | CYP1A2 (0.57) | HSP90AA1LMNAKMT2AESR2AR | |
| SCHEMBL10089372 | 0.75 | HSP90AA1 (0.56) | HSP90AA1LMNAKMT2AESR2AR | |
| SCHEMBL22795107 | 0.69 | CYP3A4 (0.50) | HSP90AA1LMNAKMT2AESR2AR | |
| SCHEMBL15912542 | 0.69 | HSP90AA1 (0.48) | HSP90AA1LMNAKMT2AESR2AR | |
| SCHEMBL4453361 | 0.65 | ALOX5 (0.58) | ESR2ALDH1A1TSHRSMN1; SMN2ALOX5 | |
| SCHEMBL4449773 | 0.64 | AHR (0.56) | ESR2ALDH1A1TSHRSMN1; SMN2ALOX5 | |
| SCHEMBL28994669 | 0.63 | ALOX5 (0.61) | ESR2ALDH1A1PGRTSHRSMN1; SMN2 | |
| SCHEMBL6854117 | 0.63 | ALOX5 (0.74) | ESR2HSD17B10ESR1PGRTSHR | |
| SCHEMBL817554 | 0.63 | ALOX5 (0.65) | ESR2ALDH1A1PGRTSHRSMN1; SMN2 | |
| SCHEMBL31222672 | 0.63 | ALOX5 (0.65) | ESR2ALDH1A1PGRTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252131-A1 | ANTIBIOTIC COMPOUNDS | AUSUBEL FREDERICK M (US) | 2020-12-17 | — | — | WO | disclosed |