SCHEMBL4453361

SCHEMBL4453361

Clc1cccc(-c2cc(Cl)cc(Cl)c2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.58
RXRA P19793 1/20 0.57
RXRB P28702 1/20 0.57
TAAR1 Q96RJ0 2/20 0.56
ESR2 Q92731 1/20 0.52
MAOB P27338 2/20 0.50
CHKA P35790 1/20 0.48
CNR1 P21554 1/20 0.47
TSHR P16473 2/20 0.47
NOTUM Q6P988 2/20 0.47
NPC1 O15118 1/20 0.47
TP53 P04637 1/20 0.47
NFKB1 P19838 1/20 0.47
RAB9A P51151 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ALDH1A1 P00352 1/20 0.46
BACE1 P56817 1/20 0.46
IDO1 P14902 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1959838 0.92 RXRA (0.59) ALOX5RXRARXRBTAAR1ESR2
SCHEMBL817554 0.91 ALOX5 (0.65) ALOX5TAAR1ESR2MAOBTSHR
SCHEMBL31222672 0.91 ALOX5 (0.65) ALOX5TAAR1ESR2MAOBTSHR
SCHEMBL29629014 0.88 ALOX5 (0.62) ALOX5TAAR1ESR2MAOBTSHR
Hydrochloric Acid SCHEMBL31070804 0.88 ALOX5 (0.62) ALOX5TAAR1ESR2MAOBTSHR
Hydrochloric Acid SCHEMBL28332867 0.88 ALOX5 (0.62) ALOX5TAAR1ESR2MAOBTSHR
SCHEMBL16394285 0.86 TAAR1 (0.71) ALOX5TAAR1ESR2MAOBBACE1
SCHEMBL31491189 0.86 TAAR1 (0.71) ALOX5TAAR1ESR2MAOBBACE1
SCHEMBL16939637 0.84 TAAR1 (0.57) ALOX5RXRARXRBTAAR1ESR2
SCHEMBL18134355 0.84 TAAR1 (0.57) ALOX5RXRARXRBTAAR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
US-20260131305-A1 MANUFACTURE OF BASALT FIBER SORBENT BOOM GAMBLE VALERIE ANN (US) 2026-05-14 US disclosed
US-20260131304-A1 BASALT FIBER SORBENT BOOM GAMBLE VALERIE ANN (US) 2026-05-14 US disclosed
US-12391580-B2 Use of basalt for adsorbing toxic material BELL, TOMARO 2025-08-19 US disclosed
US-12391579-B2 Basalt fiber for adsorbing toxic material BELL, TOMARO 2025-08-19 US disclosed
US-12384696-B2 Use of basalt fiber to adsorb toxic material BELL, TOMARO 2025-08-12 US disclosed
CN-117338229-B Wireless charging video laryngoscope 深圳天科医疗科技有限公司 2025-03-18 CN disclosed
US-20240415981-A1 GENE EDITING FOR HEMOPHILIA A WITH IMPROVED FACTOR VIII EXPRESSION CRISPR THERAPEUTICS AG (CH) 2024-12-19 US disclosed
US-20240308879-A1 USE OF BASALT FOR ADSORBING TOXIC MATERIAL BELL, TOMARO 2024-09-19 US disclosed
US-20240294399-A1 USE OF BASALT FIBER TO ADSORB TOXIC MATERIAL BELL, TOMARO 2024-09-05 US disclosed
US-20230032504-A1 TREATMENT AND REGENERATION SYSTEM AND METHOD FOR EXTRACTING ORGANIC SOLUTES FROM-WATER ABS MATERIALS, INC. 2023-02-02 US disclosed
US-11529427-B2 Gene editing for hemophilia A with improved factor VIII expression CRISPR THERAPEUTICS AG (CH) 2022-12-20 US disclosed
CN-217790036-U Multi-module sheet metal case 青岛艾诺智能仪器有限公司 2022-11-11 CN disclosed
US-11471859-B2 Treatment and regeneration system and method for extracting organic solutes from-water ABS MATERIALS, INC. (US) 2022-10-18 US disclosed
CN-111294708-B Earphone with ANC feedback microphone arranged behind speaker diaphragm GN 奥迪欧有限公司 2022-09-09 CN disclosed
US-20220259509-A1 SYSTEMS AND METHODS FOR GASIFICATION OF CARBONACEOUS MATERIALS LLT International (Ireland) Ltd. (IE) 2022-08-18 US disclosed
CN-216693192-U Wireless chargeable type floor lamp 东莞市盛祺照明科技有限公司 2022-06-07 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260131305-A1 MANUFACTURE OF BASALT FIBER SORBENT BOOM ABCB11, MAPT, STRA6 ALOX5 4357/4885RXRA 1720/4885RXRB 1913/4885
US-20260131304-A1 BASALT FIBER SORBENT BOOM ABCB11, MAPT, SULT1A1 ALOX5 4628/4885RXRA 2679/4885RXRB 2831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.