Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY8 | P40145 | 1/20 | 0.34 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12619835 | 0.91 | ADCY8 (0.36) | ADCY8ADCY1ALDH1A1NPC1RAB9A | |
| SCHEMBL12619670 | 0.91 | ADCY8 (0.36) | ADCY8ADCY1ALDH1A1NPC1RAB9A | |
| SCHEMBL12619667 | 0.87 | CYP11B1 (0.36) | ADCY8ADCY1ALDH1A1NPC1RAB9A | |
| SCHEMBL13837263 | 0.85 | HSD17B3 (0.39) | CYP11B1CYP11B2ADRB3 | |
| SCHEMBL13836984 | 0.85 | HSD17B3 (0.39) | CYP11B1CYP11B2ADRB3 | |
| SCHEMBL13837208 | 0.85 | HSD17B3 (0.39) | CYP11B1CYP11B2ADRB3 | |
| SCHEMBL11950306 | 0.84 | ALDH1A1 (0.36) | ADCY8ADCY1ALDH1A1NPC1RAB9A | |
| SCHEMBL15481338 | 0.83 | HSD17B3 (0.39) | CYP11B1CYP11B2ADRB3 | |
| SCHEMBL12620154 | 0.83 | HSD17B3 (0.39) | CYP11B1CYP11B2ADRB3 | |
| SCHEMBL24032036 | 0.83 | CYP11B1 (0.37) | ADCY8ADCY1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022034916-A1 | POLYCYCLIC AROMATIC COMPOUND | 学校法人関西学院 | 2022-02-17 | — | — | WO | disclosed |
| WO-2020251049-A1 | POLYCYCLIC AROMATIC COMPOUND | 学校法人関西学院 | 2020-12-17 | — | — | WO | disclosed |