Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23469236 | 1.00 | CPN1 (0.38) | CPN1CPB2KCNH2SHBG | |
| SCHEMBL13259733 | 0.86 | CPN1 (0.40) | CPN1CPB2KCNH2SHBG | |
| SCHEMBL13952152 | 0.85 | CPN1 (0.44) | CPN1CPB2KCNH2SHBG | |
| SCHEMBL6863922 | 0.85 | CPN1 (0.44) | CPN1CPB2KCNH2SHBG | |
| SCHEMBL13285534 | 0.83 | CPN1 (0.38) | CPN1CPB2KCNH2SHBG | |
| SCHEMBL21911259 | 0.80 | SHBG (0.41) | CPN1CPB2KCNH2SHBG | |
| SCHEMBL19881822 | 0.77 | CCR2 (0.35) | — | |
| SCHEMBL1547696 | 0.76 | CPN1 (0.47) | CPN1CPB2KCNH2SHBG | |
| SCHEMBL12913065 | 0.76 | CPN1 (0.47) | CPN1CPB2KCNH2SHBG | |
| SCHEMBL23709494 | 0.75 | CPN1 (0.40) | CPN1CPB2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252383-A2 | COMPOUNDS FOR THE MODULATION OF PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) | SRX CARDIO, LLC (US) | 2020-12-17 | — | — | WO | disclosed |