Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22797464 | 0.90 | OGA (0.33) | METAP2 | |
| SCHEMBL22797434 | 0.83 | OGA (0.34) | METAP2 | |
| SCHEMBL6839121 | 0.74 | ABCB1 (0.47) | METAP2 | |
| SCHEMBL6839119 | 0.74 | ABCB1 (0.47) | METAP2 | |
| SCHEMBL8915910 | 0.70 | — | — | |
| SCHEMBL21694335 | 0.67 | ABCB1 (0.36) | — | |
| SCHEMBL14702145 | 0.67 | OGA (0.32) | — | |
| SCHEMBL8151448 | 0.66 | ABCB1 (0.30) | — | |
| SCHEMBL7709793 | 0.66 | OGA (0.31) | — | |
| SCHEMBL3477912 | 0.65 | LGALS8 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020249663-A1 | NOVEL SPIROBICYCLIC INTERMEDIATES | JANSSEN PHARMACEUTICA NV (BE) | 2020-12-17 | — | — | WO | disclosed |