Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22797434 | 0.93 | OGA (0.34) | OGAABCB1METAP2 | |
| SCHEMBL22799862 | 0.90 | METAP2 (0.34) | METAP2 | |
| SCHEMBL6839082 | 0.72 | ABCB1 (0.49) | OGAABCB1 | |
| SCHEMBL6839079 | 0.72 | ABCB1 (0.49) | OGAABCB1 | |
| SCHEMBL21694355 | 0.72 | ABCB1 (0.49) | OGAABCB1 | |
| SCHEMBL25806714 | 0.70 | OGA (0.33) | OGA | |
| SCHEMBL25806717 | 0.70 | OGA (0.33) | OGA | |
| SCHEMBL25806719 | 0.70 | OGA (0.33) | OGA | |
| SCHEMBL22707664 | 0.70 | LMNA (0.39) | ABCB1METAP2 | |
| SCHEMBL22708264 | 0.70 | LMNA (0.39) | ABCB1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020249663-A1 | NOVEL SPIROBICYCLIC INTERMEDIATES | JANSSEN PHARMACEUTICA NV (BE) | 2020-12-17 | — | — | WO | disclosed |