Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RRM1 | P23921 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24172604 | 0.95 | C3AR1 (0.35) | SIRT6SIRT1FOLH1DPP7EPHX1 | |
| SCHEMBL23872313 | 0.95 | C3AR1 (0.35) | SIRT6SIRT1FOLH1DPP7EPHX1 | |
| SCHEMBL20104622 | 0.83 | NPY4R (0.35) | SIRT6SIRT1DPP7SMN1; SMN2MEN1 | |
| SCHEMBL22800728 | 0.83 | SIRT6 (0.35) | SIRT6SIRT1FOLH1DPP7GNAI3 | |
| SCHEMBL22799575 | 0.82 | CYP2C19 (0.39) | SIRT6SIRT1FOLH1MEN1KMT2A | |
| SCHEMBL24678191 | 0.82 | KDM4E (0.34) | SIRT6SIRT1FOLH1EPHX1 | |
| SCHEMBL24704076 | 0.82 | KISS1R (0.38) | SIRT6SIRT1FOLH1EPHX1 | |
| SCHEMBL24703969 | 0.82 | KDM4E (0.34) | SIRT6SIRT1FOLH1EPHX1 | |
| SCHEMBL24015397 | 0.81 | FURIN (0.36) | SIRT6SIRT1DPP7SMN1; SMN2KMT2A | |
| SCHEMBL19101872 | 0.81 | FURIN (0.36) | SIRT6SIRT1DPP7SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230338552-A1 | LIPID PRODRUGS OF NEUROSTEROIDS | PURETECH LYT, INC. (US) | 2023-10-26 | — | — | US | disclosed |
| US-20220395513-A1 | LIPID PRODRUGS OF NEUROSTEROIDS | PURETECH LYT, INC. (US) | 2022-12-15 | — | — | US | disclosed |
| US-20200390777-A1 | LIPID PRODRUGS OF MYCOPHENOLIC ACID AND USES THEREOF | SEAPORT THERAPEUTICS, INC. | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230338552-A1 | LIPID PRODRUGS OF NEUROSTEROIDS | CYP21A2, CYP46A1, CYP17A1 | SIRT6 2225/4885SIRT1 1981/4885FOLH1 356/4885 |
| US-20200390777-A1 | LIPID PRODRUGS OF MYCOPHENOLIC ACID AND USES THEREOF | MALT1, CYP2B6, LIPA | SIRT6 1811/4885SIRT1 3322/4885FOLH1 440/4885 |
| US-20220395513-A1 | LIPID PRODRUGS OF NEUROSTEROIDS | CYP21A2, CYP46A1, CYP17A1 | SIRT6 2225/4885SIRT1 1981/4885FOLH1 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.