Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4668605 | 0.88 | ALDH1A1 (0.79) | ALDH1A1MEN1KMT2ARECQLMDM2 | |
| SCHEMBL4668659 | 0.87 | ALDH1A1 (0.77) | ALDH1A1MEN1KMT2ARECQLMDM2 | |
| SCHEMBL22800970 | 0.86 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2APKMRECQL | |
| SCHEMBL637424 | 0.86 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2ARECQLMDM2 | |
| SCHEMBL22800910 | 0.85 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2APKMRECQL | |
| SCHEMBL4668580 | 0.85 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2APKMRECQL | |
| SCHEMBL4667808 | 0.83 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2ARECQLMDM2 | |
| SCHEMBL4667126 | 0.83 | RECQL (0.76) | ALDH1A1MEN1KMT2ARECQLMDM2 | |
| SCHEMBL22800953 | 0.83 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2APKMRECQL | |
| SCHEMBL3893257 | 0.82 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ARECQLMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11578073-B2 | Xanthine analogs as potent anti-West Nile viral agents | SOUTHERN RESEARCH INSTITUTE (US) | 2023-02-14 | — | — | US | disclosed |
| US-20200399271-A1 | XANTHINE ANALOGS AS POTENT ANTI-WEST NILE VIRAL AGENTS | OREGON HEALTH AND SCIENCE UNIVERSITY | 2020-12-24 | — | — | US | disclosed |
| CN-102807568-A | Thiadiazole derivative DPP-IV (dipeptidyl peptidase IV) inhibitor | JIANGSU CHIA TAI TIANQING PHAR | 2012-12-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200399271-A1 | XANTHINE ANALOGS AS POTENT ANTI-WEST NILE VIRAL AGENTS | XDH, PNP, MAVS | ALDH1A1 1158/4885MEN1 4456/4885KMT2A 2568/4885 |
| US-11578073-B2 | Xanthine analogs as potent anti-West Nile viral agents | XDH, PNP, MAVS | ALDH1A1 1158/4885MEN1 4456/4885KMT2A 2568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.