Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | EPHX2 | P34913 | 11/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13685610 | 0.86 | EPHX2 (0.66) | ALDH1A1TSHREPHX2MEN1KMT2A | |
| SCHEMBL2290939 | 0.82 | ALDH1A1 (1.00) | ALDH1A1TSHREPHX2P2RX7HSD17B10 | |
| SCHEMBL8338683 | 0.81 | MEN1 (0.67) | ALDH1A1TSHREPHX2MEN1KMT2A | |
| SCHEMBL1239130 | 0.81 | EPHX2 (0.56) | ALDH1A1TSHREPHX2MEN1KMT2A | |
| Iodide SCHEMBL1714835 | 0.79 | EPHX2 (0.54) | ALDH1A1TSHREPHX2MEN1KMT2A | |
| SCHEMBL14341838 | 0.78 | KMT2A (0.63) | ALDH1A1TSHREPHX2MEN1KMT2A | |
| SCHEMBL13652574 | 0.78 | KMT2A (0.68) | ALDH1A1TSHREPHX2MEN1KMT2A | |
| SCHEMBL14503280 | 0.74 | MEN1 (0.67) | ALDH1A1EPHX2MEN1KMT2AP2RX7 | |
| SCHEMBL660423 | 0.74 | ALDH1A1 (0.53) | ALDH1A1TSHREPHX2MEN1KMT2A | |
| SCHEMBL21245130 | 0.73 | EPHX2 (0.56) | ALDH1A1TSHREPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998989-B2 | 2-Imino-1,3-thiazoline-based compounds and T-type calcium channel inhibitors containing the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-08-16 | — | — | US | disclosed |
| US-20080293786-A1 | NOVEL 2-IMINO-1,3-THIAZOLINE-BASED COMPOUNDS AND T-TYPE CALCIUM CHANNEL INHIBITORS CONTAINING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293786-A1 | NOVEL 2-IMINO-1,3-THIAZOLINE-BASED COMPOUNDS AND T-TYPE CALCIUM CHANNEL INHIBITORS CONTAINING THE SAME | CACNA1I, CACNA1H, CACNA1G | ALDH1A1 2247/4885TSHR 2104/4885EPHX2 3815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.