Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11076664 | 0.83 | ALDH1A1 (0.70) | ALDH1A1TSHREPHX2HSD17B10P2RX7 | |
| SCHEMBL14644919 | 0.83 | ALDH1A1 (0.70) | ALDH1A1TSHREPHX2HSD17B10P2RX7 | |
| SCHEMBL2280187 | 0.82 | ALDH1A1 (0.69) | ALDH1A1TSHREPHX2HSD17B10P2RX7 | |
| SCHEMBL11495581 | 0.81 | ALDH1A1 (0.68) | ALDH1A1TSHREPHX2HSD17B10P2RX7 | |
| SCHEMBL660424 | 0.81 | ALDH1A1 (0.68) | ALDH1A1TSHREPHX2HSD17B10P2RX7 | |
| SCHEMBL15739698 | 0.81 | ALDH1A1 (0.68) | ALDH1A1TSHREPHX2HSD17B10P2RX7 | |
| SCHEMBL23195092 | 0.79 | ALDH1A1 (0.66) | ALDH1A1TSHREPHX2HSD17B10P2RX7 | |
| Hydrochloric Acid SCHEMBL28488097 | 0.79 | ALDH1A1 (0.66) | ALDH1A1TSHREPHX2HSD17B10P2RX7 | |
| SCHEMBL14342031 | 0.78 | ALDH1A1 (0.63) | ALDH1A1TSHREPHX2HSD17B10P2RX7 | |
| SCHEMBL14644935 | 0.78 | ALDH1A1 (0.63) | ALDH1A1TSHREPHX2HSD17B10P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998989-B2 | 2-Imino-1,3-thiazoline-based compounds and T-type calcium channel inhibitors containing the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-08-16 | — | — | US | disclosed |
| US-20080293786-A1 | NOVEL 2-IMINO-1,3-THIAZOLINE-BASED COMPOUNDS AND T-TYPE CALCIUM CHANNEL INHIBITORS CONTAINING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-11-27 | — | — | US | disclosed |
| US-20070280957-A1 | Change of the Load State of Mhc Molecules | MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN (DE) | 2007-12-06 | — | — | US | disclosed |
| US-20070280957-A1 | Change of the Load State of Mhc Molecules | MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN (DE) | 2007-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293786-A1 | NOVEL 2-IMINO-1,3-THIAZOLINE-BASED COMPOUNDS AND T-TYPE CALCIUM CHANNEL INHIBITORS CONTAINING THE SAME | CACNA1I, CACNA1H, CACNA1G | ALDH1A1 2247/4885TSHR 2104/4885EPHX2 3815/4885 |
| US-20070280957-A1 | Change of the Load State of Mhc Molecules | HLA-DRB1, MICA, CD74 | ALDH1A1 1160/4885TSHR 3260/4885EPHX2 3012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.