SCHEMBL22802235

SCHEMBL22802235

CCCCCCC(=O)C1C(=O)c2ccccc2C1=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC25A5 P05141 2/20 0.54
MEN1 O00255 1/20 0.51
NPC1 O15118 1/20 0.51
POLB P06746 1/20 0.51
GAA P10253 1/20 0.51
RAB9A P51151 1/20 0.51
KMT2A Q03164 1/20 0.51
CES2 O00748 2/20 0.46
CES1 P23141 2/20 0.46
MAPT P10636 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
HBB P68871 2/20 0.46
ALDH1A1 P00352 1/20 0.46
HSD17B10 Q99714 1/20 0.46
SOAT1 P35610 2/20 0.46
LMNA P02545 1/20 0.44
ALOX15 P16050 1/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9512613 0.93 SLC25A5 (0.57) SLC25A5MEN1NPC1POLBGAA
SCHEMBL4912246 0.81 CES2 (0.45) MEN1NPC1POLBGAARAB9A
SCHEMBL9397357 0.81 CES2 (0.50) MEN1KMT2ACES2CES1MAPT
SCHEMBL30246161 0.80 LMNA (0.55) SLC25A5POLBCES2CES1MAPT
SCHEMBL29541357 0.76 LMNA (0.44) SLC25A5MEN1POLBKMT2ACES2
SCHEMBL11354503 0.76 HTR2C (0.45) POLBGAACES2CES1MAPT
SCHEMBL13671712 0.75 SLC25A5 (0.49) SLC25A5MEN1NPC1POLBGAA
SCHEMBL29541247 0.74 LMNA (0.42) SLC25A5MEN1NPC1POLBGAA
SCHEMBL29458278 0.74 GAA (0.47) MEN1NPC1POLBGAARAB9A
SCHEMBL608005 0.74 GAA (0.47) MEN1NPC1POLBGAARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255995-A1 Nicotinyl Riboside Compounds and Their Uses MITOPOWER LLC 2023-08-17 US disclosed
EP-3986420-A1 NICOTINYL RIBOSIDE COMPOUNDS AND THEIR USES Mitopower LLC (US) 2022-04-27 EP disclosed
US-20200397807-A1 NICOTINYL RIBOSIDE COMPOUNDS AND THEIR USES MITOPOWER LLC 2020-12-24 US disclosed
WO-2020257283-A1 NICOTINYL RIBOSIDE COMPOUNDS AND THEIR USES MITOPOWER LLC (US) 2020-12-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200397807-A1 NICOTINYL RIBOSIDE COMPOUNDS AND THEIR USES NADK, NNT, NAMPT SLC25A5 178/4885MEN1 3810/4885NPC1 798/4885
US-20230255995-A1 Nicotinyl Riboside Compounds and Their Uses NADK, NNT, NAMPT SLC25A5 178/4885MEN1 3810/4885NPC1 798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.