Propylene Oxide

Propylene Oxide

SCHEMBL2280299

C=CCOCC=C.CC1CO1.OCCO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
TDP1 Q9NUW8 1/20 0.32
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylene Oxide SCHEMBL253031 0.91 ALDH1A1 (0.58) ALDH1A1TDP1MEN1POLBKMT2A
Propylene Oxide SCHEMBL1091828 0.85 ALDH1A1 (0.52) ALDH1A1TDP1MEN1POLBKMT2A
Ethylene Glycol SCHEMBL6756972 0.80 ALDH1A1 (0.74) ALDH1A1TDP1
Propylene Oxide SCHEMBL10391364 0.80 TDP1 (0.33) TDP1
Ethylene Glycol SCHEMBL29606 0.79 CA1 (0.42) ALDH1A1MEN1POLBKMT2ACA1
Ethylene Glycol SCHEMBL1643309 0.78 ALDH1A1 (0.84) ALDH1A1TDP1CA1CA2CA7
Propylene Oxide SCHEMBL3465353 0.78 ALDH1A1 (0.84) ALDH1A1TDP1MEN1POLBKMT2A
Ethylene Glycol SCHEMBL9283277 0.77 MEN1 (0.43) ALDH1A1TDP1MEN1POLBKMT2A
Ethylene Glycol SCHEMBL5612529 0.77 ALDH1A1 (0.39) ALDH1A1MEN1POLBKMT2ACA1
Ethylene Glycol SCHEMBL3902382 0.77 CA1 (0.38) ALDH1A1TDP1MEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2520579-B1 A silicone compound, photocurable liquid ink using the silicone compound, and method of manufacturing the ink RICOH CO LTD (JP) 2015-08-05 EP disclosed
US-8871861-B2 Silicone compound, photocurable liquid ink using the silicone compound, and method of manufacturing the ink RICOH COMPANY, LTD. (JP) 2014-10-28 US disclosed
US-8383314-B2 Photocurable liquid developer, method for producing the same, developing device and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-02-26 US disclosed
US-20120283378-A1 A SILICONE COMPOUND, PHOTOCURABLE LIQUID INK USING THE SILICONE COMPOUND, AND METHOD OF MANUFACTURING THE INK RICOH COMPANY, LTD., (JP) 2012-11-08 US disclosed
EP-2520579-A2 A silicone compound, photocurable liquid ink using the silicone compound, and method of manufacturing the ink Ricoh Company, Ltd. (JP) 2012-11-07 EP disclosed
EP-2348363-B1 Photocurable liquid developer, method for producing the same, developing device and image forming apparatus RICOH CO LTD (JP) 2012-08-29 EP disclosed
US-20110183254-A1 PHOTOCURABLE LIQUID DEVELOPER, METHOD FOR PRODUCING THE SAME, DEVELOPING DEVICE AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2011-07-28 US disclosed
EP-2348363-A1 Photocurable liquid developer, method for producing the same, developing device and image forming apparatus Ricoh Company, Ltd. (JP) 2011-07-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120283378-A1 A SILICONE COMPOUND, PHOTOCURABLE LIQUID INK USING THE SILICONE COMPOUND, AND METHOD OF MANUFACTURING THE INK DOT1L, L3MBTL3, KDM7A ALDH1A1 2204/4885TDP1 1935/4885MEN1 426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.