Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | WRN | Q14191 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15223884 | 0.86 | DGAT1 (0.42) | DGAT1MMP2MMP9MMP8MMP13 | |
| SCHEMBL22803402 | 0.82 | HSP90AB1 (0.40) | HSP90AB1DGAT1ALOX5MMP2MMP9 | |
| SCHEMBL20694373 | 0.80 | HSP90AB1 (0.41) | HSP90AB1DGAT1ALOX5MMP2MMP9 | |
| SCHEMBL20257915 | 0.79 | HSP90AB1 (0.40) | HSP90AB1DGAT1NCF1 | |
| SCHEMBL12033272 | 0.78 | DGAT1 (0.47) | HSP90AB1DGAT1NCF1 | |
| SCHEMBL22803422 | 0.77 | DGAT1 (0.41) | HSP90AB1DGAT1MMP2MMP9MMP8 | |
| SCHEMBL19592509 | 0.76 | DRD2 (0.43) | ALOX5NCF1 | |
| SCHEMBL20694535 | 0.76 | DGAT1 (0.40) | HSP90AB1DGAT1MMP2MMP9MMP8 | |
| SCHEMBL20806032 | 0.75 | P2RX7 (0.51) | HSP90AB1 | |
| SCHEMBL16330577 | 0.74 | DGAT1 (0.38) | HSP90AB1DGAT1CYP1A2HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120900-B2 | Polymer-bound bisacylphosphine oxides | BASF SE (DE) | 2015-09-01 | — | — | US | disclosed |
| US-8883872-B2 | Polymer-bound bisacylphosphine oxides | BASF SE (DE) | 2014-11-11 | — | — | US | disclosed |
| US-20120142805-A1 | POLYMER-BOUND BISACYLPHOSPHINE OXIDES | BASF SE (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142805-A1 | POLYMER-BOUND BISACYLPHOSPHINE OXIDES | PHOSPHO1, PARG, PEBP1 | HSP90AB1 4378/4885DGAT1 763/4885CYP1A2 4593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.