Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MDM4 | O15151 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22804086 | 1.00 | MEN1 (0.49) | MEN1RECQLKMT2AMDM4TP53 | |
| SCHEMBL120776 | 0.95 | MDM4 (0.53) | MDM4TP53SLC17A5MDM2 | |
| SCHEMBL119657 | 0.95 | MDM4 (0.53) | MDM4TP53SLC17A5MDM2 | |
| SCHEMBL15521164 | 0.89 | MDM4 (0.53) | MDM4TP53SLC17A5MDM2 | |
| SCHEMBL22804099 | 0.88 | MEN1 (0.56) | MEN1RECQLKMT2ATACR3 | |
| SCHEMBL22804088 | 0.88 | MEN1 (0.56) | MEN1RECQLKMT2ATACR3 | |
| SCHEMBL22804089 | 0.88 | MEN1 (0.56) | MEN1RECQLKMT2ATACR3 | |
| SCHEMBL5969202 | 0.87 | ADAM17 (0.51) | MDM4TP53SLC17A5MDM2 | |
| SCHEMBL1709188 | 0.87 | ADAM17 (0.51) | MDM4TP53SLC17A5MDM2 | |
| SCHEMBL1000833 | 0.87 | ADAM17 (0.51) | MDM4TP53SLC17A5MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252713-A1 | MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江智达药业有限公司 | 2020-12-24 | — | — | WO | disclosed |