SCHEMBL22804089

SCHEMBL22804089

O=C(NC(Cc1cn(C(=O)OCc2ccccc2)c2ccccc12)C(=O)O)OCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.56
▸ RECQL P46063 1/20 0.56
▸ KMT2A Q03164 1/20 0.56
▸ TACR3 P29371 1/20 0.47
▸ ITGB3 P05106 8/20 0.46
▸ ITGA2B P08514 8/20 0.46
▸ NMBR P28336 1/20 0.46
▸ TACR1 P25103 2/20 0.45
▸ CTSL P07711 1/20 0.44
▸ CTSB P07858 1/20 0.44
▸ CTSS P25774 1/20 0.44
▸ CTSK P43235 1/20 0.44
▸ CTRB1 P17538 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22804088 1.00 MEN1 (0.56) MEN1RECQLKMT2ATACR3ITGB3
SCHEMBL22804099 1.00 MEN1 (0.56) MEN1RECQLKMT2ATACR3ITGB3
SCHEMBL22804071 0.94 MEN1 (0.57) MEN1RECQLKMT2ATACR3ITGB3
SCHEMBL22804073 0.94 MEN1 (0.57) MEN1RECQLKMT2ATACR3ITGB3
SCHEMBL17959465 0.90 ADAM17 (0.53) MEN1RECQLKMT2AITGB3ITGA2B
SCHEMBL29400289 0.90 ADAM17 (0.53) MEN1RECQLKMT2AITGB3ITGA2B
SCHEMBL17959463 0.90 ADAM17 (0.53) MEN1RECQLKMT2AITGB3ITGA2B
SCHEMBL22804106 0.90 ADAM17 (0.53) MEN1RECQLKMT2AITGB3ITGA2B
SCHEMBL29400895 0.90 ADAM17 (0.53) MEN1RECQLKMT2AITGB3ITGA2B
SCHEMBL22804086 0.88 MEN1 (0.49) MEN1RECQLKMT2ATACR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 — — EP claimed
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 — — US claimed
WO-2020252713-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 浙江智达药业有限公司 2020-12-24 — — WO claimed
US-12616676-B2 Preparation method and use of modified hydrophobic excipient ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2026-05-05 — — US disclosed
EP-3988538-B1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO LTD (CN) 2024-08-07 — — EP disclosed
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 — — EP disclosed
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 — — US disclosed
US-20220110909-A1 PREPARATION METHOD AND USE OF MODIFIED HYDROPHOBIC EXCIPIENT ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 — — US disclosed
US-20220111056-A1 DRUG-LOADED EMULSION ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 — — US disclosed
WO-2020252713-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 浙江智达药业有限公司 2020-12-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616676-B2 Preparation method and use of modified hydrophobic excipient CETP, LIPA, MTTP MEN1 4516/4885RECQL 2777/4885KMT2A 855/4885
US-20220111056-A1 DRUG-LOADED EMULSION SLC43A1, SLC7A1, CETP MEN1 1927/4885RECQL 777/4885KMT2A 1926/4885
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF CETP, SLC43A1, SLC27A1 MEN1 543/4885RECQL 3116/4885KMT2A 2845/4885
US-20220110909-A1 PREPARATION METHOD AND USE OF MODIFIED HYDROPHOBIC EXCIPIENT ABCG2, CYP51A1, HACD3 MEN1 3895/4885RECQL 2848/4885KMT2A 3229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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