Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30449451 | 1.00 | EPHX2 (0.59) | EPHX2KDM4EMAPTHIF1ASLC22A6 | |
| SCHEMBL19835593 | 0.80 | EPHX2 (0.63) | EPHX2KDM4EFOLH1CA1CA2 | |
| SCHEMBL3955664 | 0.79 | EPHX2 (0.54) | EPHX2KDM4EMAPTHIF1AFOLH1 | |
| SCHEMBL11107537 | 0.78 | KDM4E (0.80) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL16560318 | 0.78 | KDM4E (0.50) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL30450105 | 0.77 | KDM4E (0.67) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL1742166 | 0.77 | KDM4E (0.67) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL30226503 | 0.76 | KDM1A (0.57) | EPHX2 | |
| SCHEMBL19983089 | 0.75 | BAZ2B (0.56) | EPHX2MAPTKCNQ3KCNQ2 | |
| SCHEMBL21531028 | 0.75 | EPHX2 (0.58) | EPHX2KDM4EFOLH1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020253824-A1 | 18F-LABELED FLUOROPICOLINYLGLYCINE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 山西医科大学第一医院 | 2020-12-24 | — | — | WO | disclosed |