Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9102180 | 0.83 | CA1 (0.53) | SMN1; SMN2NPC1RAB9AHTTLMNA | |
| SCHEMBL11818324 | 0.79 | CA1 (0.38) | SMN1; SMN2NPC1RAB9AHTTLMNA | |
| SCHEMBL11715361 | 0.77 | HTT (0.56) | SMN1; SMN2NPC1RAB9AHTTLMNA | |
| SCHEMBL5996744 | 0.76 | CA1 (0.55) | SMN1; SMN2NPC1RAB9AHTTLMNA | |
| Hydrochloric Acid SCHEMBL9506373 | 0.74 | CA1 (0.53) | SMN1; SMN2NPC1RAB9AHTTLMNA | |
| SCHEMBL11617965 | 0.72 | TSHR (0.54) | SMN1; SMN2NPC1RAB9AHTTLMNA | |
| SCHEMBL13822033 | 0.71 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL11584394 | 0.71 | — | — | |
| SCHEMBL11721552 | 0.68 | CNR2 (0.41) | SMN1; SMN2NPC1RAB9AHTTLMNA | |
| SCHEMBL11615294 | 0.67 | ALDH1A1 (0.67) | CA1CA2CA4CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020254530-A1 | 7-SULFONYL-N-(1,3,4-THIADIAZOL-2-YL)-QUINOXALINE-6-CARBOXAMIDE DERIVATIVES AND THE RESPECTIVE -BENZIMIDAZOLE-5-, -IMIDAZO[4,5-B]PYRIDINE-5-, -3H-FURO[3,2B]PYRIDINE-5-, -QUINOLINE-2-, AND -NAPHTHALENE-2-CARBOXAMIDE DERIVATIVES AS PESTICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2020-12-24 | — | — | WO | disclosed |