SCHEMBL11615294

SCHEMBL11615294

Nc1nnc(C(F)(F)C(F)(F)F)s1

nearest known ligand 0.67

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.67
FBP1 P09467 1/20 0.36
POLB P06746 2/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA13 Q8N1Q1 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
KDM4E B2RXH2 1/20 0.31
GLS O94925 2/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12186574 0.88 ALDH1A1 (0.64) ALDH1A1FBP1POLBCA12CA1
SCHEMBL294025 0.80 ALDH1A1 (1.00) ALDH1A1FBP1POLBCA12CA1
SCHEMBL2813746 0.77 ALDH1A1 (0.61) ALDH1A1FBP1POLBCA12CA1
SCHEMBL10668001 0.76 ALDH1A1 (0.67) ALDH1A1FBP1POLBCA12CA1
SCHEMBL15349261 0.76 ALDH1A1 (0.67) ALDH1A1FBP1POLBCA12CA1
SCHEMBL26132311 0.76 ALDH1A1 (0.67) ALDH1A1FBP1POLBCA12CA1
SCHEMBL15349614 0.73 ALDH1A1 (0.61) ALDH1A1FBP1POLBCA12CA1
SCHEMBL9505469 0.71 FBP1 (0.36) ALDH1A1FBP1
SCHEMBL13822033 0.71 ALDH1A1 (0.33) ALDH1A1
SCHEMBL11804342 0.71 ALDH1A1 (0.59) ALDH1A1FBP1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120077028-A Thiadiazole derivative, composition and application thereof 北京丹擎医药科技有限公司 2025-05-30 CN disclosed
WO-2024099337-A1 THIADIAZOLYL DERIVATIVES, COMPOSITIONS, AND USES THEREOF DANATLAS PHARMACEUTICALS CO., LTD. (CN) 2024-05-16 WO disclosed
EP-3227285-B1 PESTICIDALLY ACTIVE AMIDE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2022-08-10 EP disclosed
CN-107108568-B Pesticidally active amide heterocyclic derivatives with sulphur containing substituents 先正达参股股份有限公司 2021-08-10 CN disclosed
CN-107001352-B Pesticidally active amide heterocyclic derivatives with sulphur containing substituents 先正达参股股份有限公司 2021-06-04 CN disclosed
EP-3227284-B1 PESTICIDALLY ACTIVE AMIDE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2021-04-28 EP disclosed
CN-108884091-B Condensed heterocyclic compound and pest control agent 日产化学株式会社 2021-04-13 CN disclosed
US-10759815-B2 Condensed heterocyclic compounds and pesticides NISSAN CHEMICAL CORPORATION (JP) 2020-09-01 US disclosed
US-20200223868-A1 CONDENSED HETEROCLYCLIC COMPOUNDS AND PESTICIDES NISSAN CHEMICAL CORPORATION (JP) 2020-07-16 US disclosed
US-10640518-B2 Condensed heterocyclic compounds and pesticides NISSAN CHEMICAL CORPORATION (JP) 2020-05-05 US disclosed
US-10544163-B2 Condensed heterocyclic compounds and pesticides NISSAN CHEMICAL CORPORATION (JP) 2020-01-28 US disclosed
US-20190112303-A1 PESTICIDALLY ACTIVE AMIDE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2019-04-18 US disclosed
EP-3428166-A1 CONDENSED HETEROCYCLIC COMPOUND AND PEST CONTROL AGENT Nissan Chemical Corporation (JP) 2019-01-16 EP disclosed
CN-108884091-A Condensed heterocyclic compouds and noxious organism control agent 日产化学株式会社 2018-11-23 CN disclosed
US-20180327398-A1 PESTICIDALLY ACTIVE AMIDE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2018-11-15 US disclosed
US-10071997-B2 Pesticidally active amide heterocyclic derivatives with sulphur containing substituents SYNGENTA PARTICIPATIONS AG (CH) 2018-09-11 US disclosed
US-20170327495-A1 PESTICIDALLY ACTIVE AMIDE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2017-11-16 US disclosed
EP-3227285-A1 PESTICIDALLY ACTIVE AMIDE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS Syngenta Participations AG (CH) 2017-10-11 EP disclosed
WO-2016087257-A1 PESTICIDALLY ACTIVE AMIDE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2016-06-09 WO disclosed
US-4092148-A HERBICIDES AIR PRODUCTS AND CHEMICALS, INC. (US) 1978-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10071997-B2 Pesticidally active amide heterocyclic derivatives with sulphur containing substituents DDT, ACHE, GSTM1 ALDH1A1 469/4885FBP1 1077/4885POLB 4268/4885
US-10759815-B2 Condensed heterocyclic compounds and pesticides NR4A1, CHRM1, NR1D2 ALDH1A1 1097/4885FBP1 3015/4885POLB 4343/4885
US-20170327495-A1 PESTICIDALLY ACTIVE AMIDE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS DDT, ACHE, GSTM1 ALDH1A1 469/4885FBP1 1077/4885POLB 4268/4885
US-20200223868-A1 CONDENSED HETEROCLYCLIC COMPOUNDS AND PESTICIDES CHRM1, HCRTR1, NR4A1 ALDH1A1 707/4885FBP1 2356/4885POLB 4742/4885
US-10544163-B2 Condensed heterocyclic compounds and pesticides NR4A1, CHRM1, NR1D2 ALDH1A1 1147/4885FBP1 2975/4885POLB 4393/4885
US-20180327398-A1 PESTICIDALLY ACTIVE AMIDE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS DDT, ACHE, GSTM1 ALDH1A1 443/4885FBP1 1032/4885POLB 4197/4885
US-20190112303-A1 PESTICIDALLY ACTIVE AMIDE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS DDT, ACHE, GSTM1 ALDH1A1 443/4885FBP1 1032/4885POLB 4197/4885
US-10640518-B2 Condensed heterocyclic compounds and pesticides NR4A1, CHRM1, NR1D2 ALDH1A1 1121/4885FBP1 3040/4885POLB 4297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.