Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24494922 | 0.88 | CCR3 (0.51) | CCR3HRH3 | |
| SCHEMBL5872011 | 0.85 | HTR2A (0.58) | KCNH2 | |
| SCHEMBL22804380 | 0.84 | ACHE (0.55) | CCR3HRH3ACHE | |
| SCHEMBL22804418 | 0.84 | GBA1 (0.42) | — | |
| SCHEMBL24495209 | 0.81 | SPHK1 (0.63) | CCR3HRH3ACHEKCNH2 | |
| SCHEMBL2730391 | 0.78 | SIGMAR1 (0.57) | HRH3KCNH2 | |
| SCHEMBL22804323 | 0.78 | HTR2A (0.53) | HRH3ACHEKCNH2 | |
| SCHEMBL7491395 | 0.78 | SPHK1 (0.63) | CCR3HRH3ACHE | |
| SCHEMBL7321506 | 0.76 | SIGMAR1 (0.64) | CCR3HRH3 | |
| SCHEMBL15566801 | 0.76 | HTR2A (0.57) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986896-A1 | EGFR INHIBITORS FOR THE TREATMENT OF CANCER | F. Hoffmann-La Roche AG (CH) | 2022-04-27 | — | — | EP | disclosed |
| WO-2020254572-A1 | EGFR INHIBITORS FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2020-12-24 | — | — | WO | disclosed |