SCHEMBL22808709

SCHEMBL22808709

Cc1ccc(Nc2ccc(C)nc2C)c(C)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 0.42
RAB9A P51151 1/20 0.42
CCR5 P51681 1/20 0.42
CYP1A2 P05177 3/20 0.36
CCR8 P51685 1/20 0.35
GLO1 Q04760 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 2/20 0.32
NOS3 P29474 1/20 0.32
NOS2 P35228 1/20 0.32
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.31
METAP2 P50579 1/20 0.31
S100A4 P26447 1/20 0.31
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
CASP6 P55212 1/20 0.31
S1PR4 O95977 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29581994 0.82 SMN1; SMN2 (0.50) RAB9ACYP1A2ALDH1A1KDM4ETP53
SCHEMBL8307764 0.82 CCR1 (0.40) CCR1RAB9ACCR5CYP1A2CCR8
SCHEMBL19362580 0.80 KDM1A (0.50) CYP1A2ADORA2AALDH1A1KDM4ETP53
SCHEMBL20375346 0.80 PDE10A (0.43) CCR1RAB9ACCR5
SCHEMBL28492481 0.76 ALDH1A1 (0.53) RAB9ACYP1A2ALDH1A1MAPTLMNA
SCHEMBL374487 0.74 TNNI3K (0.40) RAB9ACYP1A2ALDH1A1NOS3NOS2
SCHEMBL13947026 0.73 IDO1 (0.41) CCR1RAB9ACCR5ALDH1A1MAPT
SCHEMBL10124284 0.73 ALDH1A1 (0.50) RAB9ACYP1A2ALDH1A1KDM4EMAPT
SCHEMBL13044656 0.72 IDO1 (0.42) ALDH1A1KDM4ELMNA
SCHEMBL2256034 0.72 NOS1 (0.32) CCR1RAB9ACCR5CYP1A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10873032-B2 Organic photoelectric conversion element, two-dimensional sensor, image sensor, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10873032-B2 Organic photoelectric conversion element, two-dimensional sensor, image sensor, and imaging apparatus POU2F1, PPOX, POU2F2 CCR1 3306/4885RAB9A 3037/4885CCR5 4688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.