SCHEMBL22810596

SCHEMBL22810596

CCN1c2ccccc2N(c2ccc(C)cc2)c2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.42
F2 P00734 1/20 0.42
CTSG P08311 1/20 0.42
CMA1 P23946 1/20 0.42
CTRC Q99895 1/20 0.42
MGLL Q99685 1/20 0.39
SLC6A2 P23975 5/20 0.38
LMNA P02545 1/20 0.37
TP53 P04637 1/20 0.37
MAPT P10636 4/20 0.36
MAPK1 P28482 2/20 0.36
GAA P10253 2/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TLR9 Q9NR96 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ATM Q13315 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21076086 0.86 ELANE (0.42) ELANEMGLLLMNAMAPTMAPK1
SCHEMBL27944411 0.85 FAAH (0.39) MGLLLMNAMAPTMAPK1GAA
SCHEMBL11978688 0.81 ELANE (0.50) ELANEF2CTSGCMA1CTRC
SCHEMBL13320276 0.81 MGLL (0.48) ELANEF2CTSGCMA1CTRC
SCHEMBL29699888 0.78 POLB (0.46) ELANEF2CTSGCTRCMGLL
SCHEMBL2877910 0.78
SCHEMBL474136 0.78 POLB (0.46) ELANEF2CTSGCTRCMGLL
SCHEMBL20788946 0.78 ELANE (0.46) ELANEF2CTSGCMA1CTRC
SCHEMBL6405320 0.74 CYP2A6 (0.45) ELANEF2CTSGCMA1CTRC
SCHEMBL11978693 0.74 MGLL (0.48) ELANEF2CTSGCMA1CTRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3369728-B1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND APPLICATION THEREOF IN ORGANIC ELECTROLUMINESCENT DEVICE KUNSHAN GOVISIONOX OPTOELECTRONICS CO LTD (CN) 2020-12-23 EP disclosed