SCHEMBL20788946

SCHEMBL20788946

Cc1ccc(N2c3ccccc3N(C)c3ccccc32)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.46
F2 P00734 1/20 0.46
CTSG P08311 1/20 0.46
CMA1 P23946 1/20 0.46
CTRC Q99895 1/20 0.46
MGLL Q99685 1/20 0.43
MAOA P21397 1/20 0.40
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
KMT2A Q03164 1/20 0.39
TLR9 Q9NR96 1/20 0.39
ALDH1A1 P00352 3/20 0.38
PGR P06401 1/20 0.38
TTR P02766 1/20 0.38
LMNA P02545 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
TSHR P16473 1/20 0.36
ALOX12 P18054 1/20 0.36
ACHE P22303 1/20 0.36
ADORA2A P29274 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11978688 0.86 ELANE (0.50) ELANEF2CTSGCMA1CTRC
SCHEMBL12251824 0.84 MAOA (0.44) ELANEMGLLMAOAMEN1GAA
SCHEMBL10072419 0.83 OPRK1 (0.43) MGLLMAOAMEN1GAAKMT2A
SCHEMBL12841526 0.83 OPRK1 (0.40) MGLLMAOAMEN1GAAKMT2A
SCHEMBL19001735 0.83 FAAH (0.50) MGLLMAOAMEN1KMT2AALDH1A1
SCHEMBL6405320 0.79 CYP2A6 (0.45) ELANEF2CTSGCMA1CTRC
SCHEMBL13427529 0.79 ACHE (0.37) ELANEF2CTSGCMA1CTRC
SCHEMBL12335276 0.78 F2 (0.46) ELANEF2CTSGCMA1CTRC
SCHEMBL11978693 0.78 MGLL (0.48) ELANEF2CTSGCMA1CTRC
SCHEMBL20788948 0.78 HSP90AA1 (0.52) MGLLMAOAMEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10770661-B2 Thermally activated delayed fluorescence material and application thereof in organic electroluminescence device KUNSHAN GP-VISIONOX OPTO-ELECTRONICS CO., LTD. (CN) 2020-09-08 US disclosed
US-20190074447-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND APPLICATION THEREOF IN ORGANIC ELECTROLUMINESCENCE DEVICE KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD. (CN) 2019-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190074447-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND APPLICATION THEREOF IN ORGANIC ELECTROLUMINESCENCE DEVICE KCNH1, KCNH2, KCNH3 ELANE 2054/4885F2 956/4885CTSG 3987/4885
US-10770661-B2 Thermally activated delayed fluorescence material and application thereof in organic electroluminescence device KCNH1, KCNH2, KCNH3 ELANE 2054/4885F2 956/4885CTSG 3987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.