Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14855420 | 0.85 | G6PC1 (0.46) | ALDH1A1OPRM1MEN1KMT2ASLC6A2 | |
| SCHEMBL14855136 | 0.84 | G6PC1 (0.49) | KDM4EALDH1A1OPRM1MEN1KMT2A | |
| SCHEMBL14855858 | 0.82 | G6PC1 (0.51) | KDM4EALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL3238188 | 0.82 | G6PC1 (0.51) | KDM4EALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL3240531 | 0.81 | SLC6A2 (0.44) | KDM4EALDH1A1MEN1KMT2ACHRM2 | |
| SCHEMBL20871938 | 0.80 | KDM4E (0.62) | HTR2AHTR2CKDM4EALDH1A1OPRM1 | |
| SCHEMBL12730900 | 0.75 | KMT2A (0.58) | PKMHTR2AHTR2CKDM4EALDH1A1 | |
| SCHEMBL19773700 | 0.74 | G6PC1 (0.40) | KDM4EALDH1A1OPRM1MEN1KMT2A | |
| SCHEMBL8620642 | 0.74 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3KCNH2HRH1 | |
| SCHEMBL28169437 | 0.74 | MEN1 (0.41) | ALDH1A1OPRM1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331869-B1 | MUSCARINIC AGONISTS | HEPTARES THERAPEUTICS LTD (GB) | 2020-12-23 | — | — | EP | disclosed |