Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 4/20 | 0.55 |
| ▸ | TK1 | P04183 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12956863 | 0.93 | TYMP (0.52) | TYMPTK1MAPK1HPGD | |
| SCHEMBL19412683 | 0.86 | TYMP (0.53) | TYMPTK1MAPK1HPGD | |
| SCHEMBL21783544 | 0.85 | TYMP (0.50) | TYMPTK1MAPK1HPGD | |
| SCHEMBL21100307 | 0.84 | TYMP (0.51) | TYMPTK1MAPK1HPGD | |
| SCHEMBL11472001 | 0.82 | TYMP (0.60) | TYMPTK1MAPK1HPGD | |
| SCHEMBL7139453 | 0.82 | TYMP (0.60) | TYMPTK1MAPK1HPGD | |
| SCHEMBL11472495 | 0.82 | TYMP (0.60) | TYMPTK1MAPK1HPGD | |
| SCHEMBL19259070 | 0.81 | TYMP (0.38) | TYMPTK1 | |
| SCHEMBL23873105 | 0.80 | TYMP (0.58) | TYMPTK1MAPK1HPGD | |
| SCHEMBL16380799 | 0.80 | TYMP (0.58) | TYMPTK1MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200399692-A1 | MODIFIED NUCLEOTIDES | SOLEXA LIMITED (GB) | 2020-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200399692-A1 | MODIFIED NUCLEOTIDES | ADAR, NT5C2, NSUN2 | TYMP 63/4885TK1 142/4885MAPK1 3687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.