Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 3/20 | 0.38 |
| ▸ | TK1 | P04183 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 5/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.33 |
| ▸ | GRIK5 | Q16478 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 5/20 | 0.32 |
| ▸ | MMP10 | P09238 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22815058 | 0.81 | TYMP (0.55) | TYMPTK1 | |
| SCHEMBL22815031 | 0.81 | MMP13 (0.35) | TK1KMT2AGRIA1GRIA2GRIA4 | |
| SCHEMBL19259069 | 0.77 | FGFR1 (0.30) | — | |
| SCHEMBL12956863 | 0.75 | TYMP (0.52) | TYMPTK1 | |
| SCHEMBL23341554 | 0.75 | TK2 (0.43) | TYMPTK1KMT2AGRIA1GRIA2 | |
| SCHEMBL19142038 | 0.73 | CYP1A2 (0.38) | KMT2ACYP1A2 | |
| SCHEMBL770542 | 0.72 | KMT2A (0.50) | KMT2AGRIA1GRIA2GRIA4GRIK5 | |
| SCHEMBL19171430 | 0.71 | PKM (0.52) | — | |
| SCHEMBL16427338 | 0.69 | LMNA (0.48) | TK1KMT2AGRIA1GRIA2GRIA4 | |
| SCHEMBL22814996 | 0.69 | MMP10 (0.33) | TYMPGRIA1GRIA2GRIA4GRIK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732341-B2 | Methods of delivering multiple targeting oligonucleotides to a cell using cleavable linkers | TRANSLATE BIO MA, INC. (US) | 2017-08-15 | — | — | US | disclosed |