Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25162219 | 0.90 | MMP1 (0.40) | MMP1MMP3MMP7MMP9MMP8 | |
| SCHEMBL24327263 | 0.89 | MMP1 (0.39) | MMP1MMP3MMP7MMP9MMP8 | |
| SCHEMBL26820254 | 0.87 | MMP1 (0.38) | MMP1MMP3MMP7MMP9MMP8 | |
| SCHEMBL22821674 | 0.86 | MMP1 (0.32) | MMP1MMP3MMP7MMP9MMP8 | |
| SCHEMBL13531452 | 0.85 | IDH1 (0.50) | MMP1MMP3MMP7MMP9MMP8 | |
| SCHEMBL21419451 | 0.83 | MMP1 (0.39) | MMP1MMP3MMP7MMP9MMP8 | |
| SCHEMBL21419450 | 0.83 | MMP1 (0.39) | MMP1MMP3MMP7MMP9MMP8 | |
| SCHEMBL24636658 | 0.83 | IDH1 (0.43) | MMP1MMP3MMP7MMP9MMP8 | |
| Hydrochloric Acid SCHEMBL21404876 | 0.79 | MMP1 (0.36) | MMP1MMP3MMP7MMP9MMP8 | |
| SCHEMBL24452602 | 0.77 | IDH1 (0.41) | MMP1MMP3MMP7MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983020-B1 | AGENTS FOR CLEAVING LABELS FROM BIOMOLECULES IN VIVO | TAGWORKS PHARMACEUTICALS B V (NL) | 2024-06-26 | — | — | EP | disclosed |
| WO-2020256546-A1 | COMPOUNDS FOR FAST AND EFFICIENT CLICK RELEASE | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2020-12-24 | — | — | WO | disclosed |