Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13531452 | 0.92 | IDH1 (0.50) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL22815228 | 0.83 | MMP1 (0.42) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL24452602 | 0.83 | IDH1 (0.41) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL21419468 | 0.81 | MMP1 (0.36) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL4558007 | 0.80 | ALOX5 (0.53) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL19726663 | 0.79 | MMP1 (0.40) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL19732552 | 0.79 | IDH1 (0.38) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL15314089 | 0.79 | IDH1 (0.55) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL21133311 | 0.79 | MMP1 (0.38) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL20026905 | 0.79 | MMP1 (0.38) | IDH1MMP1MMP3MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251612-A1 | 2,6-DICHLOROPHENYL ESTER COMPOUNDS AND USE THEREOF | Fusion Pharmaceuticals Inc. (CA) | 2022-12-01 | — | — | WO | disclosed |