Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 4/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13531452 | 0.90 | IDH1 (0.50) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL24636658 | 0.83 | IDH1 (0.43) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL15314089 | 0.83 | IDH1 (0.55) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL13531437 | 0.80 | IDH1 (0.53) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL13531434 | 0.80 | IDH1 (0.53) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL11990369 | 0.79 | IDH1 (0.54) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL4558007 | 0.78 | ALOX5 (0.53) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL19726663 | 0.78 | MMP1 (0.40) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL13531435 | 0.77 | IDH1 (0.49) | IDH1MMP1MMP3MMP7MMP9 | |
| SCHEMBL22815228 | 0.77 | MMP1 (0.42) | IDH1MMP1MMP3MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220160904-A1 | CHELATING PLATFORM FOR DELIVERY OF RADIONUCLIDES | FRED HUTCHINSON CANCER RESEARCH CENTER (US) | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220160904-A1 | CHELATING PLATFORM FOR DELIVERY OF RADIONUCLIDES | SLC40A1, TFRC, SLC39A14 | IDH1 1063/4885MMP1 633/4885MMP3 1216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.