Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19749316 | 0.87 | CYP19A1 (0.39) | ADAM17CYP19A1SMN1; SMN2 | |
| SCHEMBL20960393 | 0.82 | CYP19A1 (0.50) | ADAM17CYP19A1SMN1; SMN2 | |
| SCHEMBL18362386 | 0.80 | CYP19A1 (0.38) | ADAM17CYP19A1 | |
| SCHEMBL15474242 | 0.78 | CYP19A1 (0.53) | KDM4ECYP19A1SMN1; SMN2 | |
| SCHEMBL22610031 | 0.78 | CYP19A1 (0.39) | ADAM17CYP19A1SMN1; SMN2 | |
| SCHEMBL23038606 | 0.78 | CYP19A1 (0.39) | ADAM17CYP19A1SMN1; SMN2 | |
| SCHEMBL13329892 | 0.78 | ALDH1A1 (0.38) | ADAM17CYP19A1SMN1; SMN2 | |
| SCHEMBL18180516 | 0.78 | ADAM17 (0.42) | ADAM17BRD4CYP19A1 | |
| SCHEMBL16204453 | 0.78 | ALDH1A1 (0.38) | ADAM17KDM4ESMN1; SMN2 | |
| SCHEMBL25091333 | 0.77 | CYP19A1 (0.54) | CYP19A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983020-B1 | AGENTS FOR CLEAVING LABELS FROM BIOMOLECULES IN VIVO | TAGWORKS PHARMACEUTICALS B V (NL) | 2024-06-26 | — | — | EP | disclosed |
| WO-2020256545-A1 | AGENTS FOR CLEAVING LABELS FROM BIOMOLECULES IN VIVO | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2020-12-24 | — | — | WO | disclosed |
| WO-2020256546-A1 | COMPOUNDS FOR FAST AND EFFICIENT CLICK RELEASE | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2020-12-24 | — | — | WO | disclosed |