Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | PRKACA | P17612 | 2/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.35 |
| ▸ | PRKX | P51817 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.35 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.35 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.35 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.35 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3403490 | 0.83 | NQO2 (0.40) | TAS1R3TAS1R1ROCK2PRKACAIRAK1 | |
| SCHEMBL22821577 | 0.82 | TAS1R3 (0.39) | TAS1R3TAS1R1LMNAROCK2PRKACA | |
| SCHEMBL27409546 | 0.79 | HTT (0.39) | TAS1R3TAS1R1MAPK1BACE1HTT | |
| SCHEMBL23897626 | 0.78 | TAS1R3 (0.39) | TAS1R3TAS1R1LMNABACE1HTT | |
| SCHEMBL30358364 | 0.78 | HTT (0.40) | TAS1R3TAS1R1ROCK2PRKACAIRAK1 | |
| SCHEMBL4609315 | 0.78 | TAS1R3 (0.38) | TAS1R3TAS1R1LMNAROCK2PRKACA | |
| SCHEMBL22815235 | 0.78 | BACE1 (0.43) | TAS1R3TAS1R1LMNAROCK2PRKACA | |
| SCHEMBL4582151 | 0.77 | NPC1 (0.39) | TAS1R3TAS1R1LMNAMAPK1HTT | |
| SCHEMBL8764309 | 0.76 | TPMT (0.45) | TAS1R3TAS1R1LMNAROCK2PRKACA | |
| SCHEMBL8978043 | 0.76 | PARP1 (0.38) | TAS1R3TAS1R1LMNAROCK2PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020256546-A1 | COMPOUNDS FOR FAST AND EFFICIENT CLICK RELEASE | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2020-12-24 | — | — | WO | disclosed |