Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | PRKACA | P17612 | 2/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.35 |
| ▸ | PRKX | P51817 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.35 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.35 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.35 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.35 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4839012 | 0.78 | LMNA (0.53) | LMNATAS1R3TAS1R1ROCK2PRKACA | |
| SCHEMBL3403490 | 0.77 | NQO2 (0.40) | TAS1R3TAS1R1ROCK2PRKACAIRAK1 | |
| SCHEMBL22815249 | 0.76 | TAS1R3 (0.36) | LMNATAS1R3TAS1R1ROCK2PRKACA | |
| SCHEMBL28453111 | 0.76 | HTT (0.47) | TPMTLMNATAS1R3TAS1R1ROCK2 | |
| SCHEMBL22815235 | 0.76 | BACE1 (0.43) | LMNATAS1R3TAS1R1ROCK2PRKACA | |
| SCHEMBL15358753 | 0.76 | TAS1R3 (0.38) | LMNATAS1R3TAS1R1ROCK2PRKACA | |
| SCHEMBL4609315 | 0.76 | TAS1R3 (0.38) | LMNATAS1R3TAS1R1ROCK2PRKACA | |
| SCHEMBL30358364 | 0.76 | HTT (0.40) | TAS1R3TAS1R1ROCK2PRKACAIRAK1 | |
| SCHEMBL8413046 | 0.73 | HDAC1 (0.40) | TAS1R3TAS1R1ROCK2PRKACAIRAK1 | |
| SCHEMBL22821577 | 0.73 | TAS1R3 (0.39) | LMNATAS1R3TAS1R1ROCK2PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782565-A1 | IODINATED X-RAY-CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1997-07-09 | — | — | EP | disclosed |
| WO-1996009285-A1 | IODINATED X-RAY-CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1996-03-28 | — | — | WO | disclosed |