Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 2/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3403490 | 0.91 | NQO2 (0.40) | KDM4EALDH1A1NQO2TAS1R3TAS1R1 | |
| SCHEMBL8413046 | 0.83 | HDAC1 (0.40) | NQO2TAS1R3TAS1R1ROCK2RPS6KA5 | |
| SCHEMBL3649580 | 0.80 | F3 (0.49) | PARP1KDM4EALDH1A1F3TAS1R3 | |
| SCHEMBL9266883 | 0.80 | KDM4E (0.36) | KDM4EALDH1A1NQO2TAS1R3TAS1R1 | |
| SCHEMBL4609315 | 0.79 | TAS1R3 (0.38) | KDM4EALDH1A1TAS1R3TAS1R1POLB | |
| SCHEMBL9265836 | 0.78 | SERPINE1 (0.44) | KDM4EALDH1A1HTTLMNAGAA | |
| SCHEMBL14777914 | 0.78 | ALDH1A1 (0.43) | KDM4EALDH1A1LMNAGAAROCK2 | |
| SCHEMBL29234296 | 0.76 | ALDH1A1 (0.44) | PARP1KDM4EALDH1A1LMNAGAA | |
| SCHEMBL30945842 | 0.76 | ALDH1A1 (0.44) | PARP1KDM4EALDH1A1LMNAGAA | |
| SCHEMBL22815249 | 0.76 | TAS1R3 (0.36) | TAS1R3TAS1R1POLBTDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707572-A1 | IODINATED OLIGOMERIC COMPOUNDS AND DIAGNOSTIC COMPOSITIONS CONTAINING THE SAME | BRACCO S.p.A. (IT) | 1996-04-24 | — | — | EP | disclosed |