Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 7/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22816232 | 0.91 | TP53 (0.49) | AKR1C3TP53AKR1C2ALOX15L3MBTL1 | |
| SCHEMBL28047000 | 0.91 | AKR1C3 (0.55) | AKR1C3AKR1C2ALOX15L3MBTL1POLB | |
| SCHEMBL18241057 | 0.90 | CYP19A1 (0.45) | AKR1C3TP53AKR1C2ALOX15L3MBTL1 | |
| SCHEMBL22816144 | 0.89 | TP53 (0.43) | AKR1C3TP53AKR1C2ALOX15L3MBTL1 | |
| SCHEMBL22816581 | 0.88 | TP53 (0.47) | AKR1C3TP53ALOX15L3MBTL1POLB | |
| SCHEMBL22816200 | 0.87 | POLB (0.42) | AKR1C3TP53AKR1C2ALOX15L3MBTL1 | |
| SCHEMBL22816662 | 0.85 | MARS1 (0.43) | AKR1C3TP53ALOX15L3MBTL1POLB | |
| SCHEMBL21296984 | 0.85 | AKR1C3 (0.49) | AKR1C3ALOX15L3MBTL1POLBMEN1 | |
| SCHEMBL22816841 | 0.84 | AKR1C3 (0.48) | AKR1C3TP53AKR1C2ALOX15L3MBTL1 | |
| SCHEMBL22816536 | 0.83 | AKR1C3 (0.47) | AKR1C3ALOX15L3MBTL1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |