Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22816232 | 0.90 | TP53 (0.49) | TP53ALOX15L3MBTL1AKR1C3POLB | |
| SCHEMBL22816146 | 0.90 | CYP19A1 (0.44) | TP53ALOX15L3MBTL1AKR1C3POLB | |
| SCHEMBL22815682 | 0.89 | AKR1C3 (0.47) | TP53ALOX15L3MBTL1AKR1C3POLB | |
| SCHEMBL22816581 | 0.87 | TP53 (0.47) | TP53ALOX15L3MBTL1AKR1C3POLB | |
| SCHEMBL22816200 | 0.86 | POLB (0.42) | TP53ALOX15L3MBTL1AKR1C3POLB | |
| SCHEMBL22816662 | 0.84 | MARS1 (0.43) | TP53ALOX15L3MBTL1AKR1C3POLB | |
| SCHEMBL21296920 | 0.83 | NPBWR1 (0.51) | ALOX15L3MBTL1AKR1C3POLBMEN1 | |
| SCHEMBL22815921 | 0.83 | NPBWR1 (0.41) | TP53ALOX15L3MBTL1AKR1C3POLB | |
| SCHEMBL23484637 | 0.82 | NPBWR1 (0.53) | TP53ALOX15L3MBTL1AKR1C3POLB | |
| SCHEMBL28047000 | 0.81 | AKR1C3 (0.55) | ALOX15L3MBTL1AKR1C3POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |