Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2279107 | 0.85 | MAPT (0.47) | SMN1; SMN2LMNAMAPTGABRPGABRD | |
| SCHEMBL2272168 | 0.82 | AKR1C3 (0.52) | SMN1; SMN2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2272174 | 0.82 | AKR1C3 (0.52) | SMN1; SMN2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL13052583 | 0.81 | MEN1 (0.46) | SMN1; SMN2LMNAMAPTNNMTMKNK1 | |
| Hydrochloric Acid SCHEMBL2274905 | 0.81 | AKR1C3 (0.50) | SMN1; SMN2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1259194 | 0.78 | CYP19A1 (0.42) | SMN1; SMN2LMNAMAPTHDAC1HDAC6 | |
| SCHEMBL1259189 | 0.78 | CYP19A1 (0.42) | SMN1; SMN2LMNAMAPTHDAC1HDAC6 | |
| SCHEMBL30996071 | 0.76 | NOS2 (0.45) | SMN1; SMN2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL13052584 | 0.76 | TUBB4A (0.39) | SMN1; SMN2LMNAMAPTMAP3K7TAB1 | |
| SCHEMBL3629872 | 0.73 | CA12 (0.56) | SMN1; SMN2MAPTMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190283-A1 | Fab I Inhibitors | DEBIOPHARM INTERNATIONAL SA (CH) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190283-A1 | Fab I Inhibitors | SERPINB1, TFPI, TFPI2 | SMN1; SMN2 4421/4885LMNA 3308/4885MAPT 3629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.