Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | PDE8B | O95263 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23319912 | 0.88 | ALOX15 (0.58) | ALOX15L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL21248338 | 0.86 | ALOX15 (0.56) | ALOX15L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL22815786 | 0.86 | ALOX15 (0.56) | ALOX15L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL17351879 | 0.86 | ALOX15 (0.56) | ALOX15L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL22608424 | 0.85 | ALOX15 (0.55) | ALOX15L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL7822911 | 0.84 | CYP19A1 (0.55) | ALOX15L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL21296920 | 0.82 | NPBWR1 (0.51) | ALOX15L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL13815987 | 0.82 | HPGD (0.69) | MEN1KMT2AHPGDCYP1A2SMN1; SMN2 | |
| SCHEMBL28950371 | 0.82 | ALOX15 (0.52) | ALOX15L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL27830497 | 0.82 | ALOX15 (0.52) | ALOX15L3MBTL1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112399873-A | Triazole glycolate oxidase inhibitor | 奥凡生物科技公司 | 2021-02-23 | — | — | CN | disclosed |
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |