Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 4/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | PDE8B | O95263 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22815761 | 0.90 | CCR2 (0.50) | NPBWR1ALOX15L3MBTL1AKR1C3KMT2A | |
| SCHEMBL21296928 | 0.89 | ALOX15 (0.49) | NPBWR1ALOX15L3MBTL1AKR1C3KMT2A | |
| SCHEMBL22815786 | 0.87 | ALOX15 (0.56) | ALOX15L3MBTL1AKR1C3KMT2AMEN1 | |
| SCHEMBL22815906 | 0.87 | ALOX15 (0.47) | NPBWR1ALOX15L3MBTL1AKR1C3KMT2A | |
| SCHEMBL22816607 | 0.87 | CCR2 (0.47) | NPBWR1ALOX15L3MBTL1AKR1C3KMT2A | |
| SCHEMBL22815736 | 0.87 | MAPT (0.48) | NPBWR1ALOX15L3MBTL1AKR1C3KMT2A | |
| SCHEMBL23319956 | 0.87 | NPBWR1 (0.51) | NPBWR1ALOX15L3MBTL1AKR1C3KMT2A | |
| SCHEMBL21296893 | 0.86 | CYP19A1 (0.56) | NPBWR1ALOX15L3MBTL1KMT2AMEN1 | |
| SCHEMBL23484637 | 0.86 | NPBWR1 (0.53) | NPBWR1ALOX15L3MBTL1AKR1C3KMT2A | |
| SCHEMBL22816232 | 0.86 | TP53 (0.49) | NPBWR1ALOX15L3MBTL1AKR1C3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11389456-B2 | Compounds and methods for treating oxalate-related diseases | OXALURX, INC. (US) | 2022-07-19 | — | — | US | disclosed |
| US-20200390778-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. | 2020-12-17 | — | — | US | disclosed |
| WO-2019165159-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. (US) | 2019-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200390778-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | XDH, PNPO, LOX | NPBWR1 2573/4885ALOX15 127/4885L3MBTL1 2663/4885 |
| US-11389456-B2 | Compounds and methods for treating oxalate-related diseases | XDH, PNPO, LOX | NPBWR1 2573/4885ALOX15 127/4885L3MBTL1 2663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.