Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 2/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 4/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22817348 | 0.84 | PRKCQ (0.34) | PRKCQCHRNA7HRH3GRM5ALDH1A1 | |
| SCHEMBL24728224 | 0.82 | NR3C1 (0.34) | KARS1ZAP70CHRNA7ALDH1A1 | |
| SCHEMBL24728147 | 0.81 | ZAP70 (0.32) | KARS1ZAP70 | |
| SCHEMBL12804137 | 0.71 | CFB (0.36) | GRM5REN | |
| SCHEMBL4484912 | 0.70 | AHR (0.47) | GRM5RENTNFRIPK1 | |
| SCHEMBL4574265 | 0.69 | ALDH1A1 (0.59) | STK17AHRH3ALDH1A1HTTKDM4E | |
| SCHEMBL2983533 | 0.69 | ALDH1A1 (0.38) | GRM5RENALDH1A1 | |
| SCHEMBL4798726 | 0.68 | CYP1A2 (0.40) | GRM5RENKDM4E | |
| SCHEMBL14526754 | 0.66 | REN (0.38) | GRM5REN | |
| SCHEMBL1436944 | 0.66 | ALDH1A1 (0.49) | STK17AHRH3ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257495-A1 | INHIBITORS OF ERYTHROCYTE BAND 3 TYROSINE PHOSPHORYLATION AND USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2020-12-24 | — | — | WO | disclosed |