Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 3/20 | 0.46 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623917 | 0.82 | THRA (0.48) | MAPK1L3MBTL1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL7888296 | 0.80 | MAPT (0.44) | SMN1; SMN2KDM4ETOP2ATOP2BMAPT | |
| SCHEMBL18118665 | 0.78 | KMT2A (0.56) | MAPK1L3MBTL1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL5182173 | 0.77 | SMN1; SMN2 (0.51) | MAPK1L3MBTL1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL5705535 | 0.76 | MAPT (0.50) | L3MBTL1KDM4ELMNATDP1KMT2A | |
| SCHEMBL304176 | 0.76 | TDP1 (0.78) | MAPK1L3MBTL1LMNATDP1KMT2A | |
| SCHEMBL7276062 | 0.76 | FFAR1 (0.74) | LMNACYP1A2CYP2C19TDP1FFAR1 | |
| Bicarbonate SCHEMBL7699565 | 0.75 | TDP1 (0.75) | MAPK1L3MBTL1LMNATDP1KMT2A | |
| SCHEMBL28207503 | 0.75 | TDP1 (0.75) | MAPK1L3MBTL1LMNATDP1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28588274 | 0.75 | TDP1 (0.75) | MAPK1L3MBTL1LMNATDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200399683-A1 | Composition and Methods For Affinity Directed Enrichment of Rare Species | SPARK MOLECULAR DIAGNOSTICS, INC. | 2020-12-24 | — | — | US | disclosed |