Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 8/20 | 0.48 |
| ▸ | THRB | P10828 | 8/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623903 | 0.87 | THRA (0.54) | THRATHRBL3MBTL1ESR1NR3C1 | |
| SCHEMBL22817985 | 0.82 | MAPK1 (0.50) | MAPK1L3MBTL1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL4624544 | 0.81 | PSMB8 (0.39) | THRATHRBSMN1; SMN2KDM4ELMNA | |
| SCHEMBL4625987 | 0.75 | THRA (0.56) | THRATHRBMAPK1L3MBTL1KDM4E | |
| SCHEMBL1603232 | 0.75 | KMT2A (0.42) | SMN1; SMN2KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL18118665 | 0.75 | KMT2A (0.56) | MAPK1L3MBTL1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL9631380 | 0.73 | TDP1 (0.47) | L3MBTL1SMN1; SMN2KDM4ELMNATDP1 | |
| SCHEMBL8875118 | 0.72 | SMN1; SMN2 (0.41) | THRBMAPK1L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL7533840 | 0.72 | TDP1 (0.42) | L3MBTL1SMN1; SMN2KDM4ELMNATDP1 | |
| SCHEMBL7533211 | 0.71 | GLRA1 (0.47) | L3MBTL1SMN1; SMN2KDM4ELMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242622-B1 | MONITORING OLIGONUCLEOTIDE BINDING PROCESSES USING CHEMILUMINESCENCE QUENCHING | MOLECULAR LIGHT TECH RES LTD (GB) | 2008-06-18 | — | — | EP | disclosed |
| US-7169554-B2 | Monitoring oligonucleotide binding processes using chemiluminescence quenching | GEN-PROBE INCORPORATED (US) | 2007-01-30 | — | — | US | disclosed |
| US-20030082713-A1 | Monitoring oligonucleotide binding processes using chemiluminescence quenching | THIRD WAVE TECHNOLOGIES, INC. | 2003-05-01 | — | — | US | disclosed |