Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5705535 | 0.82 | MAPT (0.50) | MAPTPDE10AALDH1A1KDM4E | |
| SCHEMBL7894547 | 0.81 | MAPT (0.42) | MAPTALDH1A1TP53 | |
| SCHEMBL22817985 | 0.80 | MAPK1 (0.50) | MAPTALDH1A1TOP2ATOP2BSMN1; SMN2 | |
| SCHEMBL27507766 | 0.80 | MAPT (0.39) | MAPTALDH1A1KDM4E | |
| SCHEMBL7889880 | 0.80 | BCHE (0.43) | MAPTPDE10AALDH1A1TAAR1ITGB1 | |
| SCHEMBL7893003 | 0.79 | HTR4 (0.50) | HTR2A | |
| SCHEMBL7797045 | 0.79 | MAPT (0.48) | MAPTPDE10AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL7045154 | 0.79 | MAPT (0.56) | MAPTPDE10AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8149705 | 0.79 | MAPT (0.56) | MAPTALDH1A1SMN1; SMN2TP53KDM4E | |
| SCHEMBL8151119 | 0.79 | MAPT (0.55) | MAPTALDH1A1SMN1; SMN2TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6171520-B1 | Reagents for labeling SH groups, process for the preparation of them and method for labeling with them | SS PHARMACEUTICAL CO., LTD. (JP) | 2001-01-09 | — | — | US | disclosed |
| US-6080591-A | USEFUL IN BIOLOGICAL ASSAYS FOR DETERMINATION OF VITAMIN B12, FOLATE, CORTISOL, ESTRADIOL, AND THROMBOXANE B2 | BAYER CORPORATION (US) | 2000-06-27 | — | — | US | disclosed |
| EP-0844246-A1 | REAGENTS FOR LABELING SH GROUPS, PROCESS FOR THE PREPARATION OF THEM, AND METHOD FOR LABELING WITH THEM | SS Pharmaceutical Co., Ltd. (JP) | 1998-05-27 | — | — | EP | disclosed |
| US-5663074-A | INCUBATION OF FOLATE WITH AMINE REACTIVE COMPOUND, ACTIVATION AND INCUBATION THE ACRIDINIUM ESTER-FOLATE CONJUGATE | CHIRON DIAGNOSTICS CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| US-5241070-A | Biological analysis | CIBA CORNING DIAGNOSTICS CORP. (US) | 1993-08-31 | — | — | US | disclosed |