Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 3/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21387943 | 0.82 | RXFP1 (0.58) | RXFP1ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL1900214 | 0.79 | RXFP1 (0.66) | RXFP1ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL13757702 | 0.76 | PARP14 (0.55) | RXFP1ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL18814515 | 0.73 | ALDH1A1 (0.62) | RXFP1ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL29191666 | 0.71 | PARP14 (0.49) | ALDH1A1HPGDKDM4EMAPTKMT2A | |
| SCHEMBL18097910 | 0.71 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL1805658 | 0.71 | RXFP1 (0.56) | RXFP1ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL8923243 | 0.71 | ALDH1A1 (0.66) | RXFP1ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL1122552 | 0.71 | TRPV1 (0.58) | RXFP1ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL9607557 | 0.70 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EPARP14MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020254322-A1 | NEW TRICYCLIC 5-HT2 ANTAGONISTS | ANAMAR AB (SE) | 2020-12-24 | — | — | WO | disclosed |