Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23568147 | 0.85 | CRHBP (0.60) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL25489732 | 0.79 | CRHBP (0.54) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL446420 | 0.76 | CRHBP (0.48) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL30887358 | 0.76 | CRHBP (0.50) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL24442811 | 0.76 | CRHBP (0.50) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL30503055 | 0.76 | CRHBP (0.50) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL27024549 | 0.74 | CRHBP (0.48) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL24608790 | 0.73 | CRHBP (0.47) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL15678829 | 0.73 | CRHBP (0.47) | CRHBPCRHR2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL458236 | 0.72 | ALDH1A1 (0.48) | CRHBPCRHR2ALDH1A1MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252867-A1 | LONG-LIFE DARK-BLUE FLUORESCENT DOPING MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE (OLED) | 南京高光半导体材料有限公司 | 2020-12-24 | — | — | WO | disclosed |