Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25489732 | 0.89 | CRHBP (0.54) | CRHBPCRHR2AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL30887358 | 0.85 | CRHBP (0.50) | CRHBPCRHR2AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL22819599 | 0.85 | CRHBP (0.50) | CRHBPCRHR2AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL24442811 | 0.85 | CRHBP (0.50) | CRHBPCRHR2AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL30503055 | 0.85 | CRHBP (0.50) | CRHBPCRHR2AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL27024549 | 0.83 | CRHBP (0.48) | CRHBPCRHR2AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL29662848 | 0.79 | APEX1 (0.67) | CRHBPCRHR2AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL25295329 | 0.78 | CRHBP (0.52) | CRHBPCRHR2AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL22717286 | 0.77 | CRHBP (0.62) | CRHBPCRHR2AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL457778 | 0.76 | ESR2 (0.52) | CRHBPCRHR2AKR1C2AKR1C1AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255792-A | Organic compound and application thereof, and organic electroluminescent device comprising organic compound | 北京鼎材科技有限公司 | 2024-06-28 | — | — | CN | disclosed |
| US-20240209006-A1 | ORGANIC COMPOUND, LIGHT-EMITTING ELEMENT, AND DISPLAY PANEL | SHENZHEN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) | 2024-06-27 | — | — | US | disclosed |
| US-20230157170-A1 | HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | UDC IRELAND LIMITED (IE) | 2023-05-18 | — | — | US | disclosed |
| US-20230157170-A1 | HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | UDC IRELAND LIMITED (IE) | 2023-05-18 | — | — | US | disclosed |
| US-20230104248-A1 | POLYCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | UDC IRELAND LIMITED (IE) | 2023-04-06 | — | — | US | disclosed |
| CN-114539296-A | Boron-containing organic compound and application thereof | 北京鼎材科技有限公司 | 2022-05-27 | — | — | CN | disclosed |
| WO-2021185712-A1 | HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-09-23 | — | — | WO | disclosed |
| WO-2021185829-A1 | HETEROCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-09-23 | — | — | WO | disclosed |
| WO-2021122740-A1 | POLYCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230104248-A1 | POLYCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | VDAC2, VDAC3, KCNC1 | CRHBP 3678/4885CRHR2 3847/4885AKR1C2 3383/4885 |
| US-20240209006-A1 | ORGANIC COMPOUND, LIGHT-EMITTING ELEMENT, AND DISPLAY PANEL | NR2E3, NR2C2, NR4A2 | CRHBP 1464/4885CRHR2 194/4885AKR1C2 1446/4885 |
| US-20230157170-A1 | HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | DDT, CTCF, EED | CRHBP 3773/4885CRHR2 4063/4885AKR1C2 2675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.