Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.60 |
| ▸ | MEN1 | O00255 | 8/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22819976 | 0.92 | LMNA (0.57) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL22820170 | 0.88 | KMT2A (0.67) | KMT2AMEN1NPC1RAB9AHTT | |
| SCHEMBL22820075 | 0.85 | HTT (0.61) | KMT2AMEN1NPC1RAB9AHTT | |
| SCHEMBL22820117 | 0.82 | CYP1A2 (0.64) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL22820172 | 0.82 | HPGD (0.64) | KMT2AMEN1NPC1RAB9AHTT | |
| SCHEMBL22819966 | 0.81 | ALDH1A1 (0.70) | KMT2AMEN1NPC1RAB9AHTT | |
| SCHEMBL27879746 | 0.81 | MEN1 (0.62) | KMT2AMEN1NPC1RAB9ARXFP1 | |
| SCHEMBL22819969 | 0.80 | KMT2A (0.60) | KMT2AMEN1NPC1RAB9ATDP1 | |
| SCHEMBL3715237 | 0.80 | KMT2A (0.68) | KMT2AMEN1NPC1RAB9AHTT | |
| SCHEMBL22819939 | 0.80 | LMNA (0.70) | KMT2AMEN1NPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020255425-A1 | ANTI-HBV AGENT | 国立研究開発法人理化学研究所 | 2020-12-24 | — | — | WO | disclosed |