SCHEMBL22823271

SCHEMBL22823271

c1ccc(N(c2ccccc2)c2ccc(-c3cc4c(s3)C3(c5ccccc5Sc5ccccc53)c3cc(-c5ccc(N(c6ccccc6)c6ccccc6)cc5)sc3C43c4ccccc4Sc4ccccc43)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 2/20 0.38
▸ MAPT P10636 2/20 0.32
▸ KDM4E B2RXH2 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ CYP1A2 P05177 1/20 0.31
▸ CYP3A4 P08684 1/20 0.31
▸ CYP2D6 P10635 1/20 0.31
▸ CYP2C9 P11712 1/20 0.31
▸ CYP2C19 P33261 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22823269 0.92 APP (0.32) APPMAPT
SCHEMBL22823397 0.87 — —
SCHEMBL22822930 0.87 GAA (0.34) MAPTKDM4EALDH1A1CYP1A2CYP3A4
SCHEMBL22823628 0.86 APP (0.40) APPMAPTKDM4EALDH1A1CYP1A2
SCHEMBL22823503 0.85 APP (0.39) APPMAPTKDM4EALDH1A1CYP1A2
SCHEMBL22823182 0.85 APP (0.39) APPMAPTKDM4EALDH1A1CYP1A2
SCHEMBL22822899 0.84 APP (0.38) APPMAPTKDM4EALDH1A1CYP1A2
SCHEMBL22823616 0.83 — —
SCHEMBL22823371 0.83 APP (0.37) APPMAPTKDM4EALDH1A1CYP1A2
SCHEMBL22822942 0.82 LOXL2 (0.35) MAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12048245-B2 Compound, organic light-emitting element including the same, display panel and display device WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2024-07-23 — — US disclosed
US-12048245-B2 Compound, organic light-emitting element including the same, display panel and display device WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2024-07-23 — — US disclosed
US-20200403161-A1 COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT INCLUDING THE SAME, DISPLAY PANEL AND DISPLAY DEVICE WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2020-12-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200403161-A1 COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT INCLUDING THE SAME, DISPLAY PANEL AND DISPLAY DEVICE TRMT1L, TLK1, TSPO APP 952/4885MAPT 134/4885KDM4E 2905/4885
US-12048245-B2 Compound, organic light-emitting element including the same, display panel and display device TRMT1L, TLK1, TSPO APP 952/4885MAPT 134/4885KDM4E 2905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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