Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22823925 | 0.79 | THRB (0.35) | THRBLMNA | |
| SCHEMBL21789849 | 0.72 | — | — | |
| SCHEMBL14155256 | 0.72 | — | — | |
| SCHEMBL9558965 | 0.67 | THRB (0.33) | THRBLMNA | |
| SCHEMBL17049376 | 0.65 | — | — | |
| SCHEMBL13183710 | 0.65 | CTSK (0.40) | THRBLMNA | |
| SCHEMBL12124914 | 0.65 | CTSK (0.37) | THRBLMNA | |
| SCHEMBL20803766 | 0.63 | — | — | |
| SCHEMBL18555364 | 0.63 | — | — | |
| SCHEMBL2668083 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020254831-A1 | BICYCLIC HETEROCYCLIC COMPOUNDS AS INHIBITORS OFBCDIN3D ACTIVITY | STORM THERAPEUTICS LTD (GB) | 2020-12-24 | — | — | WO | disclosed |