Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.31 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22829801 | 1.00 | ACHE (0.38) | ACHETSHRCYP3A4TDP1ALDH1A1 | |
| SCHEMBL1155735 | 0.89 | TSHR (0.43) | ACHETSHRCYP3A4TDP1ALDH1A1 | |
| SCHEMBL301240 | 0.81 | CYP3A4 (0.45) | ACHETSHRCYP3A4TDP1ALDH1A1 | |
| SCHEMBL10412404 | 0.79 | CYP3A4 (0.43) | ACHETSHRCYP3A4TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28963440 | 0.79 | CYP3A4 (0.43) | ACHETSHRCYP3A4TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1581895 | 0.77 | CYP3A4 (0.41) | ACHETSHRCYP3A4TDP1ALDH1A1 | |
| Bromide SCHEMBL1582990 | 0.77 | CYP3A4 (0.41) | ACHETSHRCYP3A4TDP1ALDH1A1 | |
| SCHEMBL18979106 | 0.75 | RIPK1 (0.34) | TSHRCYP3A4TDP1CA1CA2 | |
| SCHEMBL1156372 | 0.75 | TSHR (0.43) | ACHETSHRCYP3A4TDP1ALDH1A1 | |
| SCHEMBL49618 | 0.75 | CYP3A4 (0.52) | ACHETSHRCYP3A4TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200407381-A1 | C-BULKY P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | Université de Bourgogne (FR) | 2020-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200407381-A1 | C-BULKY P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | PLCG1, PLCG2, ACHE | ACHE 3/4885TSHR 3498/4885CYP3A4 834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.