SCHEMBL22830876

SCHEMBL22830876

O=C1N[C@H]2[C@H](CS[C@H]2CCCCC(=O)O[C@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H](O)[C@@H]2O)N1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 6/20 0.55
▸ MEN1 O00255 1/20 0.51
▸ ABL1 P00519 1/20 0.51
▸ LMNA P02545 1/20 0.51
▸ PKM P14618 1/20 0.51
▸ IDE P14735 1/20 0.51
▸ MAPK1 P28482 1/20 0.51
▸ KMT2A Q03164 1/20 0.51
▸ RIN1 Q13671 1/20 0.51
▸ L3MBTL1 Q9Y468 1/20 0.51
▸ HLCS P50747 6/20 0.50
▸ FGF1 P05230 1/20 0.46
▸ FGF2 P09038 1/20 0.46
▸ VEGFA P15692 1/20 0.46
▸ HPSE Q9Y251 1/20 0.46
▸ PLCD1 P51178 1/20 0.46
▸ F2 P00734 1/20 0.42
▸ PRSS1 P07477 1/20 0.42
▸ PRSS2 P07478 1/20 0.42
▸ PRSS3 P35030 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27849533 0.88 TDP1 (0.56) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL1270497 0.85 TDP1 (0.62) TDP1MEN1ABL1LMNAPKM
SCHEMBL17727882 0.83 TDP1 (0.67) TDP1MEN1ABL1LMNAPKM
SCHEMBL28434108 0.78 TDP1 (0.72) TDP1MEN1ABL1LMNAPKM
SCHEMBL22290232 0.75 TDP1 (0.82) TDP1MEN1ABL1LMNAPKM
SCHEMBL20500199 0.75 TDP1 (0.58) TDP1MEN1ABL1LMNAPKM
SCHEMBL20280629 0.75 TDP1 (0.58) TDP1MEN1ABL1LMNAPKM
SCHEMBL27832339 0.74 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
SCHEMBL21176811 0.74 TDP1 (0.81) TDP1MEN1ABL1LMNAPKM
SCHEMBL21114407 0.74 TDP1 (0.81) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2552202-B1 METHODS AND COMPOSITIONS FOR WEIGHT LOSS SDG INC (US) 2023-07-26 — — EP claimed
CN-111712236-A Compositions comprising lipid-based nanoparticles for the treatment of diabetes SDG公司 2020-09-25 — — CN claimed
CN-110612114-A Lipid-based nanoparticles with enhanced stability SDG公司 2019-12-24 — — CN claimed
CN-101237854-B Lipid construct for delivery of insulin to a mammal SDG INC 2013-03-27 — — CN claimed
CN-101237854-A Lipid construct for delivery of insulin to a mammal SDG INC (US) 2008-08-06 — — CN claimed
CN-101237855-A Lipid construct for delivery of interferon to a mammal SDG INC (US) 2008-08-06 — — CN claimed
US-11517529-B2 Orally bioavailable lipid-based constructs SDG, INC. (US) 2022-12-06 — — US disclosed
US-20200405638-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS SDG INC (US) 2020-12-31 — — US disclosed
CN-111712236-A Compositions comprising lipid-based nanoparticles for the treatment of diabetes SDG公司 2020-09-25 — — CN disclosed
CN-110612114-A Lipid-based nanoparticles with enhanced stability SDG公司 2019-12-24 — — CN disclosed
CN-101237854-B Lipid construct for delivery of insulin to a mammal SDG INC 2013-03-27 — — CN disclosed
CN-101237855-A Lipid construct for delivery of interferon to a mammal SDG INC (US) 2008-08-06 — — CN disclosed
CN-101237854-A Lipid construct for delivery of insulin to a mammal SDG INC (US) 2008-08-06 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11517529-B2 Orally bioavailable lipid-based constructs FABP2, FABP1, FABP6 TDP1 4819/4885MEN1 966/4885ABL1 4375/4885
US-20200405638-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, FABP6 TDP1 4819/4885MEN1 966/4885ABL1 4375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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