SCHEMBL22831706

SCHEMBL22831706

O=C(O)c1ccc(C(F)(F)F)c(S)c1O

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SELL P14151 1/20 0.48
SELP P16109 1/20 0.48
ALB P02768 1/20 0.40
ALDH1A1 P00352 3/20 0.40
HPGD P15428 3/20 0.40
KDM4E B2RXH2 2/20 0.40
HSD17B10 Q99714 2/20 0.40
MAPT P10636 2/20 0.39
HDAC8 Q9BY41 1/20 0.39
DAO P14920 1/20 0.39
ASPH Q12797 1/20 0.39
CES2 O00748 2/20 0.38
LDHA P00338 1/20 0.38
CYP1A2 P05177 1/20 0.37
CLCN2 P51788 1/20 0.36
MMP2 P08253 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TAS2R14 Q9NYV8 2/20 0.36
NOTUM Q6P988 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9700677 0.86 SELL (0.54) SELLSELPALBALDH1A1HPGD
SCHEMBL29276539 0.80 ALDH1A1 (0.46) ALDH1A1HPGDKDM4EHSD17B10MAPT
SCHEMBL8621898 0.80 TAS2R14 (0.44) ALDH1A1HPGDKDM4EHSD17B10MAPT
SCHEMBL29276538 0.80 CLCN2 (0.44) ALDH1A1HPGDKDM4EHSD17B10MAPT
SCHEMBL22075506 0.79 SELL (0.45) SELLSELPALBALDH1A1HPGD
SCHEMBL2320900 0.79 ALB (0.46) SELLSELPALBALDH1A1HPGD
SCHEMBL22462327 0.76 HDAC4 (0.49) ALDH1A1KDM4EHSD17B10MAPT
SCHEMBL7278483 0.76 TAS2R14 (0.50) ALBALDH1A1HPGDKDM4EMAPT
SCHEMBL176255 0.74 SELL (0.79) SELLSELPALBALDH1A1HPGD
SCHEMBL29860525 0.74 SELL (0.79) SELLSELPALBALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12286425-B2 Herbicidally active bicyclic benzamides BAYER AKTIENGESELLSCHAFT (DE) 2025-04-29 US disclosed
CN-111788199-B Herbicidally active bicyclic benzamides 拜耳公司 2024-05-03 CN disclosed
EP-3759105-B1 HERBICIDALLY ACTIVE SUBSTITUTED BICYCLIC BENZOYLAMIDES BAYER AG (DE) 2022-04-06 EP disclosed
US-20200404920-A1 HERBICIDALLY ACTIVE BICYCLIC BENZAMIDES BAYER AKTIENGESELLSCHAFT (DE) 2020-12-31 US disclosed
CN-111788199-A Herbicidally active bicyclic benzamides 拜耳公司 2020-10-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12286425-B2 Herbicidally active bicyclic benzamides CBR3, CBR1, AOX1 SELL 4800/4885SELP 4853/4885ALB 3164/4885
US-20200404920-A1 HERBICIDALLY ACTIVE BICYCLIC BENZAMIDES CBR3, CBR1, AOX1 SELL 4800/4885SELP 4853/4885ALB 3164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.